{"id":40,"date":"2022-12-09T16:03:31","date_gmt":"2022-12-09T16:03:31","guid":{"rendered":"https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/?page_id=40"},"modified":"2023-03-14T10:55:49","modified_gmt":"2023-03-14T10:55:49","slug":"outreach","status":"publish","type":"page","link":"https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/society\/outreach\/","title":{"rendered":"Outreach"},"content":{"rendered":"<!-- Preview block -->\n<img loading=\"lazy\" width=\"100%\" height=\"100%\" src=\"\"\/>\n\n<div class=\"block-banner \" data- style=\"background-image: url(https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/MCastanho_BBB-01.png)\">\n    <div class=\"inner-container\">\n      <div class=\"text-box\">\n        <h2 class=\"title\">Public &#038; Media<\/h2>\n        <div class=\"text\">\n          <p>Outreach<\/p>\n\n        <\/div>\n      <\/div>\n    <\/div>\n<\/div>\n\n<style type=\"text\/css\">\n  [data-] {\n    background: ;\n    color: ;\n  }\n<\/style>\n\n\n\n\n<h4>July 22 <span style=\"color:#da1c5c\" class=\"has-inline-color\">|<\/span> World Brain Day<\/h4>\n\n\n\n<p>The World Federation of Neurology, a non-governmental organization was established on July 22th 1957. It was suggested by the Public Awareness and Advocacy Committee that 22th July 2014 should be celebrated as \u201cWorld Brain Day\u201d. The Board of Trustees meeting in February 2014 endorsed this proposal as an annual activity. The objective is to improve awareness and advocacy for brain health globally. On World Brain Day, we advocate for health care, education, and research into neurological disorders.<\/p>\n\n\n\n<p>The theme for 2022 campaign is \u201cour brain, our future\u201d.<\/p>\n\n\n\n<ul><li><strong>What are the challenges and progress in the development of drugs for the brain?<\/strong><br>Activa magazine (Health)<\/li><\/ul>\n\n\n\n<p>\u201cIn response to the challenge of developing new drugs to treat diseases associated with the brain, we and other researchers have focused on strategies that use the natural transporters or receptors of the barrier cells. There are already some therapeutic antibodies modified to recognize and take advantage of the \u201cride\u201d of a blood-brain barrier receptor that is involved in iron transport, for example.<\/p>\n\n\n\n<p>These antibodies, which are in advanced stages of development, are intended to treat diseases such as Alzheimer&#8217;s and Hunter syndrome. At iMM, our research group, led by Professor Miguel Castanho, is using compounds derived from a natural protein, which work like a key (i.e. recognizes an attribute in the cells of the barrier, which works like a lock, and manages to have \u201cpermission\u201d to enter the brain).<\/p>\n\n\n\n<p>Our compound has been shown to be able to cross the blood-brain barrier, and is therefore being used to modify advanced drugs, such as antibodies and nanoparticles, with therapeutic potential in the brain. We have a special focus on viral infections in the central nervous system, brain metastases from breast cancer and early diagnosis of Alzheimer&#8217;s disease.\u201d <\/p>\n\n\n\n<p>Please read the full article (in Portuguese) <a href=\"https:\/\/activa.sapo.pt\/diz-quem-sabe\/2022-07-22-quais-os-desafios-e-progressos-no-desenvolvimento-de-farmacos-para-o-cerebro\/\" target=\"_blank\" rel=\"noreferrer noopener\">here<\/a>.<\/p>\n\n\n\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column\">\n<div class=\"wp-block-image is-style-rounded\"><figure class=\"aligncenter size-medium\"><img loading=\"lazy\" width=\"300\" height=\"295\" src=\"https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2023\/03\/Vera-Neves_BBB-Site-300x295.png\" alt=\"\" class=\"wp-image-229\" srcset=\"https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2023\/03\/Vera-Neves_BBB-Site-300x295.png 300w, https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2023\/03\/Vera-Neves_BBB-Site-1024x1008.png 1024w, https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2023\/03\/Vera-Neves_BBB-Site-768x756.png 768w, https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2023\/03\/Vera-Neves_BBB-Site-1536x1512.png 1536w, https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2023\/03\/Vera-Neves_BBB-Site.png 1839w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/><\/figure><\/div>\n\n\n\n<p style=\"font-size:17px\">Opinion article by Vera Neves, PhD. Researcher at the Instituto de Medicina Molecular Jo\u00e3o Lobo Antunes (iMM).<\/p>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-background is-style-wide\" style=\"background-color:#da1c5c;color:#da1c5c\"\/>\n\n\n\n<h4>May 28 <span style=\"color:#da1c5c\" class=\"has-inline-color\">|<\/span> International Day of Action for Women\u2019s Health<\/h4>\n\n\n\n<p>In 1987, during a reunion of members of WGNRR in Costa Rica, May 28 was declared as International Day of Action for Women\u2019s Health (also known as International Women\u2019s Health Day). Since then, May 28 has been internationally renowned and activities are held worldwide by women\u2019s and health organizations globally to educate people about women\u2019s rights to their bodies and to health, as well as to equality and non-discrimination.<\/p>\n\n\n\n<ul><li><strong>Focused on the most fearsome breast cancer<\/strong><br>Lux Woman magazine (Health)<\/li><\/ul>\n\n\n\n<p>Despite some advances, breast cancer remains one of the biggest challenges in this modern medicine. An international consortium, led by Prof. Miguel Castanho, is making efforts to give answers to one of the most aggressive forms of this disease \u2013 the triple negative breast cancer. The ambition is to create a more effective and safer drug, not only against the tumor itself, but also against its fearsome brain metastases. <\/p>\n\n\n\n<p>Please read the full article (in Portuguese) <a href=\"https:\/\/www.luxwoman.pt\/focados-no-cancro-de-mama-mais-temivel\/)\" target=\"_blank\" rel=\"noreferrer noopener\">here<\/a>.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-full is-resized\"><img loading=\"lazy\" src=\"https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/Group.jpg\" alt=\"\" class=\"wp-image-188\" width=\"465\" height=\"310\" srcset=\"https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/Group.jpg 620w, https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/Group-300x200.jpg 300w\" sizes=\"(max-width: 465px) 100vw, 465px\" \/><figcaption>In the photo (from left to right) researchers from the Instituto de Medicina Molecular Jo\u00e3o Lobo Antunes (iMM), Marco Cavaco, Vera Neves and Miguel Castanho, responsible for the project \u201cProtecting the Brain from Metastatic Breast Cancer\u201d, funded by the \u201cla Caixa&#8221; Foundation and Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia (FCT).<\/figcaption><\/figure><\/div>\n\n\n\n<ul><li><strong>Fight against breast cancer: contribution of Portuguese Science<br><\/strong>Sa\u00fade e Bem Estar (Health and Wellness)<\/li><\/ul>\n\n\n\n<p><strong>INNOVATIVE DRUG UNDER DEVELOPMENT<br><\/strong>It is important to reflect on the research effort of Portuguese scientists in the area of women&#8217;s health. At Instituto de Medicina Molecular Jo\u00e3o Lobo Antunes (iMM), we are working on the development of an innovative drug that combines antitumor activity (i.e capable of destroying triple negative breast tumor cells) with the ability to enter the brain and thus eliminate brain metastases. The goal is to create a new drug that can, in the future, be used in the treatment of breast cancer, without severe adverse effects, and capable of preventing the progression of brain metastases. With this work, we intend to contribute with an effective solution to a problem that persists and affects many women, despite advances in the fight against other types of cancer. Please read the full article (in Portuguese) <a href=\"https:\/\/saudebemestar.com.pt\/luta-contra-o-cancro-da-mama-contributo-da-ciencia-portuguesa\/)\" target=\"_blank\" rel=\"noreferrer noopener\">here<\/a>.<\/p>\n\n\n\n<div class=\"wp-block-columns\">\n<div class=\"wp-block-column\" style=\"flex-basis:33.33%\">\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" width=\"231\" height=\"346\" src=\"http:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/Miguel-Castanho.jpg\" alt=\"\" class=\"wp-image-189\" srcset=\"https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/Miguel-Castanho.jpg 231w, https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/Miguel-Castanho-200x300.jpg 200w\" sizes=\"(max-width: 231px) 100vw, 231px\" \/><\/figure>\n<\/div>\n\n\n\n<div class=\"wp-block-column\" style=\"flex-basis:66.66%\"><\/div>\n<\/div>\n\n\n\n<p style=\"font-size:17px\">Opinion article by Prof. Dr. Miguel Castanho. Principal Investigator at the Instituto de Medicina Molecular Jo\u00e3o Lobo Antunes (iMM) and professor at the Faculty of Medicine of Lisbon. He leads several international projects, among them the project \u201cProtecting the Brain from Metastatic Breast Cancer\u201d, financed by the \u201cla Caixa\u201d Foundation and Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia (FCT).<\/p>\n\n\n\n<hr class=\"wp-block-separator has-text-color has-background is-style-wide\" style=\"background-color:#da1c5c;color:#da1c5c\"\/>\n\n\n\n<h4>February 4 <span style=\"color:#da1c5c\" class=\"has-inline-color\">|<\/span> World Cancer Day<\/h4>\n\n\n\n<p>World Cancer Day aims to prevent millions of deaths each year by raising awareness and education about cancer, and pressing governments and individuals across the world to act against the disease.<\/p>\n\n\n\n<p>Marco Cavaco explains our project &#8220;Protecting the brain from metastatic breast cancer&#8221; in Sa\u00fade Mais channel. Please watch <a href=\"https:\/\/www.saudemais.tv\/video\/259885--t07-e013-02-1?fbclid=IwAR2vG_aYcza09SL85R-IvM_d2OP5knID9qvr8WbMioSafchleX_IFp03Jy8\" target=\"_blank\" rel=\"noreferrer noopener\">here<\/a>.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" src=\"http:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/Marco-Cavaco_VF-1024x473.png\" alt=\"\" class=\"wp-image-191\" width=\"768\" height=\"355\" srcset=\"https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/Marco-Cavaco_VF-1024x473.png 1024w, https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/Marco-Cavaco_VF-300x139.png 300w, https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/Marco-Cavaco_VF-768x355.png 768w, https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/Marco-Cavaco_VF.png 1439w\" sizes=\"(max-width: 768px) 100vw, 768px\" \/><\/figure><\/div>\n\n\n\n<p class=\"has-white-color has-text-color\">.<\/p>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large is-resized\"><img loading=\"lazy\" src=\"https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/Rodape-la-Caixa-e-FCT-1024x289.png\" alt=\"\" class=\"wp-image-123\" width=\"512\" height=\"145\" srcset=\"https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/Rodape-la-Caixa-e-FCT-1024x289.png 1024w, https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/Rodape-la-Caixa-e-FCT-300x85.png 300w, https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/Rodape-la-Caixa-e-FCT-768x216.png 768w, https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/wp-content\/uploads\/sites\/36\/2022\/12\/Rodape-la-Caixa-e-FCT.png 1348w\" sizes=\"(max-width: 512px) 100vw, 512px\" \/><\/figure><\/div>\n","protected":false},"excerpt":{"rendered":"<p>July 22 | World Brain Day The World Federation of Neurology, a non-governmental organization was established on July 22th 1957. It was suggested by the Public Awareness and Advocacy Committee that 22th July 2014 should be celebrated as \u201cWorld Brain Day\u201d. The Board of Trustees meeting in February 2014 endorsed this proposal as an annual &hellip; <a href=\"https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/society\/outreach\/\">Continued<\/a><\/p>\n","protected":false},"author":13,"featured_media":0,"parent":20,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"views\/template-900.blade.php","meta":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v17.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Outreach - BREAST-BRAIN-N-BBB<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/breast-brain-n-bbb.imm.medicina.ulisboa.pt\/society\/outreach\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Outreach - BREAST-BRAIN-N-BBB\" \/>\n<meta property=\"og:description\" content=\"July 22 | World Brain Day The World Federation of Neurology, a non-governmental organization was established on July 22th 1957. 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